According to Box Office Mojo, as of right now, Transformers has made $262,541,048 worldwide. I hate to burst your bubble, but a number of non-sequels have made more than that worldwide. You may have heard of "Titanic", "Mrs. Doubtfire", or even "Waterworld", for example.This movie has made more money then any movie that was not a sequel.
In other words it has made the most money of any movie that has just been released.
What? That is not "in other words". It's a totally different proposition, and still inaccurate. Spiderman, The Da Vinci Code, and 300 are some of the non-sequels that had larger opening weekends.