Scientists are making progressive headway in understanding the process of aging and discovering how natural bioactives can play a significant role in delaying the aging process and the onset of age-related diseases.
Natural bioactive components are found in plants, animal and marine life. A major break-through in anti-aging research is the identification of novel bioactives which, when consumed in small amounts, directly affect significant physiological activity in the body to promote good health.
Natural Bioactives
Resveratrol - In 2006, Resveratrol, a phytochemical found in red grapes, made news headlines for an anti-aging pill that could one day, increase human life span and promote health 1-2. While current research is still inconclusive, the demand for Resveratrol supplements continues to grow. Popular for its high antioxidant potency, Resveratrol is known to support heart health, promote immunity, stamina and boost blood flow to the brain.
Vitamin D - In 2009, an American team of scientists won the Nobel Peace Prize for their research on telomeres. Telomeres are the protective ends of DNA strands, considered to be a predictor of age-related disease. According to a study published in the American Journal of Clinical Nutrition3 a higher intake of Vitamin D was associated with maintenance of telomere length possibly extending human life span by 5 years compared to those whose intake of Vitamin D was less.
Caretenoids - The caretenoids, lutein and zeaxanthin, are found in high concentration in the retina and lens of the eye. Epidemiological studies 4-5 reveal that lutein and zeaxanthin may play a positive role in preventing age-related macular degeneration and cataracts.
Choline - The cognitive health market is a priority among the senior generation with B vitamins, particularly choline, among the more popular natural bioactives. Choline shows efficacy in improving memory and a deficiency of choline is related to poor memory performance 6.
Omega 3 fatty acids - help to improve cognitive functions and behavior. According to Framingham Heart Study, an intake of 180 mg of DHA a day was associated with a 50 percent reduction in dementia. 7-8 A regular intake of fish oil supplements is also associated with improving age-related joint pains.
Natural Eggshell Membrane (NEM) a newly researched bioactive ingredient that supports joint health. An eight-week study conducted on 67 patients showed significant improvement in joint pain and stiffness after just 10 days of supplementation 9.
Private Labeling Natural Bioactives
Anti-aging supplements are highly popular with seniors and the 77.3 million baby boomers comprising 30 percent of the American population (U.S. Census Bureau). This demographics account for 15 percent of the sale of specialty dietary supplements that target specific health conditions related to aging.
For more information on how you can easily meet the consumer needs of this large audience with innovative anti-aging supplements, contact a knowledgeable private label supplement manufacturer with a GMP-certified facility.
Vitacap Labs provides private labeled anti-aging supplements which can be marketed to provide a variety of health benefits to a growing aging population. Those looking to manufacture small order quantities will find Vitacap Labs flexible production runs, as low as 96 bottles, a unique advantage.
References:
1. Baur JA, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006 Nov 16;444(7117):337-42.
2. Pearson KJ, et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab 2008 Aug;8(2):157-68.
3. American Journal of Clinical Nutrition, Vol. 86, No. 5, 1420-1425, November 2007
4. Ma L, Lin XM. Effects of lutein and zeaxanthin on aspects of eye health. J Sci Food Agric 2010 Jan 15;90(1):2-12. )
5. Parisi V, et al. Carotenoids and antioxidants in age-related maculopathy italian study: multifocal electroretinogram modifications after 1 year. Ophthalmology 2008 Feb;115(2):324-333.]
6. Wong-Goodrich SJ, et al. Spatial memory and hippocampal plasticity are differentially sensitive to the availability of choline in adulthood as a function of choline supply in utero. Brain Res 2008 Oct 27;1237:153-66.
7. Johnson EJ, Schaefer EJ. Potential role of dietary n-3 fatty acids in the prevention of dementia and macular degeneration. Am J Clin Nutr 2006 Jun;83(6 Suppl):1494S-1498S.
8. Vaisman N, Kaysar N, Zaruk-Adasha Y, Pelled D, Brichon G, Zwingelstein G, Bodennec J. Correlation between changes in blood fatty acid composition and visual sustained attention performance in children with inattention: effect of dietary n-3 fatty acids containing phospholipids. Am J Clin Nutr 2008 May;87(5):1170-80.
9. Crowley DC, et al. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int J Med Sci 2009 Oct;6(1):312-21.
Natural Bioactives – Putting Youth on Hold!
