My concern with sugar substitutes is more the fact that they have 0 calories. It just seems really unnatural to me. I mean, if they're not being broken down like other foods are, what are they doing? (Personally, I have no problems with eating cloned animals, at least not right now. It's a little weird, but doesn't seem unsafe.)
The choice between what I call "A Bad Choice Set" (Refined white Sugar and Artificial sweetners) is a personal one. Most love sweetened items, so one has a decision to make one way or the other.
One has to weigh the pros and cons on health effects--as well as--the pros and cons within the goals one seeks. The way to make progress is to educate yourself on the subject matter.
I have posted information on Splenda and refined white sugar in the past. To be fair, table sugar has a rather long history of use therefore a longer medical review time. In contrast, Splenda hasnt been out "commercially" that long (though chemically it was made over 30 years ago), and the jury is still out because of this fact (though there are some listed health effects). I have studied both, and I have come to personal terms with Splenda, though I see ones argument--of course.
One of the "main" reasons I choose Splenda is primarily due to no calories and it satisfies my sweet tooth and fits within my diet framework. One can bake with it as well as use it for other food items where one cant with other types of sweetners.
If you google both refined white sugar and Splenda, you will get a wealth of information on these two items. Be careful which sites you go to and look for objective and unbiased information.
Pesonally, I stay away from ALL SUGAR including honey, and this CAN be tough if you dont know what you are eating. When I say I stay away from sugar I mean things like: refined white sugar, commercial brown sugar, High Fructose Corn Syrup, and other forms of sugars like this. I wanted to clarify this because I dont know your knowledge of "sugars". I prefer to get my carbs (converted to a form of sugar in the blood) from fruits (simple sugars) and complex carbs from Oatmeal and Long Grain Brown Rice, for example.
One has to make some hard decisions when trying to diet and eat healthy. It can "easily" confuse and drive one to the fricken nut farm. Make some decisions, keep reading and obtaining knowledge, and make more hard decisions on-the-fly toward your goal, and PREVENT confusion and frustration from killing your motivation toward your purpose.
Best wishes to you my friend,
Chillen