Question about genetics

Theoretically speaking, if a fat person with poor past muscle building genetics starts working out and gets into shape, will his children have better "muscle building" genetics, or is genetics something that can't change over generations?

And if a person with great genetics lets himself go and get fat and unhealthy, does the fat and unhealthy genes get past to his children?
 
Theoretically speaking, if a fat person with poor past muscle building genetics starts working out and gets into shape, will his children have better "muscle building" genetics, or is genetics something that can't change over generations?

Are there genetic tendencies in family's? Sure, can we manipulate these tendencys? Maybe, though I'm not aware of a definitive answer.

And if a person with great genetics lets himself go and get fat and unhealthy, does the fat and unhealthy genes get past to his children?
A normal sized child who has over sized parents is many more times likely to become obese in their lifetime. Compared to childen with moderatly fit parents.
^This is the greater factor when compared to genetics.
Lifestyle and how the parents teach their children about how to eat, exercise and show by example. Is by far the most important aspect.
 
To your first Q, no. The idea was thought to be true in the past, when Larmarck said that giraffe's necks would grow longer from generation to generation because they stretched to get higher and higher leaves. But he turned out to be wrong when natural selection came into play. Think about it, taller neck giraffes mate with taller neck giraffes and make a taller neck giraffe. If something was to happen to the lower leaves most of the shorter neck giraffes would die, leaving only long necks to mate with other long necks. After many generations of tall neck giraffe mating and the leaves getting higher, only the tallest neck giraffes would survive.

If you take two enormous human beings, odds are if they mate, they'll make a large baby. Not 100%, but more than likely. And certain phenotypes offer advantages and disadvantages which make up natural selection.
 
Yay, I've wanted to answer this question for a while.

This is a question of epigenetic imprinting, and yes it is possible. Here's how it goes. We have DNA, everyone pretty much knows that. We are born with a combination of DNA from our mother and father. DNA tells our body how to grow and how to generate cells. What was recently discovered was that we have what is called epi-DNA or literally (above the DNA). It tells which parts of our genes to function and to what extent. While the DNA we were born with cannot change, our epigenetic functioning can change due to outside factors.

A study was done with mice. Soon to be mother mice, not yet mated, were separated into two groups. One group was given a healthy supplemented diet and the other was not. The mice were then impregnated and the offspring were very different. The ones with the unhealthy mother had lower glucose tolerance and a higher occurrence of cancer, they also had a yellow coat whereas the offspring of the healthy mother had darker brown coats. I'm not sure, but I believe the diets of the mother mice were the same while they were pregnant. So basically, what the mother ate before she was pregnant affected her offspring.

Another example of this is with identical twins. Identical twins have identical DNA, but their epiDNA is only identical shortly after they are conceived. Outside factors effect each of the twins epiDNA differently. A study was done on twin 4 year old boys and twin 74 year old women. The epiDNA of the 4 year olds was nearly identical while the epiDNA of the 74 year olds was very different. Different life experiences and health habits affected the twins in different ways. This is why sometimes one twin will end up taller or one will be more likely to get cancer. Lifestyle and habits actually change part of your genes.

So here's a warning, if you're planning on having children, but don't think your nasty habits like smoking, excessive drinking, drug use, unhealthy eating, or excessive stress will effect your future children as long as you don't do it when you're pregnant (If you're a woman), think again. If you are a man or a woman, anything that you do when you're young will effect your children. Fortunately, it doesn't have drastic effects. My grandmother smoked since about the age of 12 and during her pregnancy with my dad. I turned out fine, I think. It probably did have some tiny effect on me though :(.

I think the opposite works too. If you're healthy and exercise, then those traits will probably be passed on too.

I'm no expert on this stuff, and there really isn't much out there about it yet. It's pretty new research. But it provides an alternative to the idea the natural selection is the only explanation for evolution. Natural selection really doesn't explain much these days since most of the population is able to procreate.

I hope that helped!
 
Last edited:
Here's a picture of the mice!

Each one was born from the same species of mother mouse. The only difference is the mother of the yellow one was unhealthy before pregnancy and the mother of the brown one was healthy.

There really is more than just natural selection. How does one explain the fact that less and less of us are being born with wisdom teeth? Natural selection cannot explain it. It's not like we are choosing our mates based on whether or not they had wisdom teeth. And those of us with wisdom teeth aren't dying out before we have a chance to mate. There's so much more to be learned about genetics.
 
Last edited:
That's a huge fallacy.. Asking a question that has nothing to do with epigenetics or natural selection? Transgenerational epigenetic inheritance is still way up in the air. Personally I don't believe that you can change your genetic make up over the coarse of a generation. Maybe, maybe you can change gene expression a slight amount, but even this is far away from being fact.
 
I really can't figure out what it is you are arguing. Like I said, there's still a lot we don't know, and natural selection is definitely not the only answer.
 
Doing healthy things will affect the baby in the womb, yes. But being an unhealthy person because of the choices YOU make will not automatically make your child to be predisposed to being unhealthy. Making yourself fat won't change your genes and make your kids fat. If you were already predisposed to fat gain, because it was in your genes to begin with, you might pass it on to your kids.

If you were born skinny and weak and made yourself into a hulking beast of muscle, your kids will probably be born skinny and weak.


If you are an amputee, your baby won't be born without arms.
 
If you were born skinny and weak and made yourself into a hulking beast of muscle, your kids will probably be born skinny and weak.
Dammit. That is exactly my case.

Now it's just a matter of mating with someone with good genes and a roll of the dice.
 
Forget that...

Having ****ty genes is a huge reason I'm the way I am today. If I were naturally athletic and studly, I would probably take it for granted.
 
yeah, it's very basic genetics. Your babies are a product of your (you and your partners) genes. As they grow up, environment will kick inn (what the kid eats, who he hangs out with, etc).
 
I know this topic is a little old but can someone enlighten me on a couple of issues

1) It's been widely reported that things like smoking and mobile phone use alters your DNA. Does this then mean that your DNA can get damaged but not improved?

2) If we can change our muscular structue through hyperplasia then why wouldn't our genic blueprint change to reflect that? It is our blueprint after all. If I were made up of 50/50 type 1 & 2 fibres last year but have adapted to 40/60 this year then surely this change would have occured because of a genetic instruction and therefore becoming part of my genetic identity( see genetic response paragraph)


I'm no expert so not trying to contradict anyone, I'm just trying to understand why our DNA doesn't change when our muscle composition changes. :)
 
1) DNA can probobly be improved. I don't know if we do it yet on humans, but we can cut and paste DNA, and fix things. Alot of etical dilammas here..

2) Your genes won't change because of how you train or new tissue grows. It's like saying if my hair grows long my kid will have long hair too. Or if I injure myself and scar tissue grows, my kid will have scar tissue too.
Now, you might be able to "activate" genes that have been "sleeping" before by doing stuff (I'm not quite sure) but you can't make new genes just like that. If I grow huge biceps, my kid won't have huge biceps just like that.



Smoking can mess with our genes, I know that, there was an example in my biology text book, but I don't have it here..
 
1) DNA can probobly be improved. I don't know if we do it yet on humans, but we can cut and paste DNA, and fix things. Alot of etical dilammas here..

2) Your genes won't change because of how you train or new tissue grows. It's like saying if my hair grows long my kid will have long hair too. Or if I injure myself and scar tissue grows, my kid will have scar tissue too.
Now, you might be able to "activate" genes that have been "sleeping" before by doing stuff (I'm not quite sure) but you can't make new genes just like that. If I grow huge biceps, my kid won't have huge biceps just like that.

With the first point, what I was trying to show is that our DNA changes naturally all the time. Bearing this in mind is it still imposible for us to guide the changes which take place purely through the way we lead our lives?

2) It's not quite the same because I'm talking about body composition not size of muscle or length of hair. You can get big biceps through hypertrophy but if you changed your body from being type 1 dominant to type 2 dominant through hyperplasia then you're dealing with a change in the way your body is designed. You've effectively given your body an engine change so surely it no longer reflects the original plans and new plans must have been drawn up

I'll tell you what, my first daughter born 3 years ago was born with my 'skinny' genes. I'll talk to my girlfriend tonight and see if she's up for making another baby so we can see if my change in body comp is now reflected in my DNA ;)
 
1. They mutate your DNA, and yes there can be beneficial mutations.
2. You're slightly altering your phenotype, but if you were to stop lifting your body would naturally go back in the direction it was before you started lifting.
 
1. They mutate your DNA, and yes there can be beneficial mutations.
2. You're slightly altering your phenotype, but if you were to stop lifting your body would naturally go back in the direction it was before you started lifting.

Phenotype? Sorry but I'm a genetics dumbass, I got about 45% in my human genetics exam :(. Do you mean that a change to the phenotype can't carry over to the genotype?
 
Last edited:
Don't worry, I found a site that explained it in simple terms
 
Back
Top