Hello iamjboi, welcome to the forum and well done on your level of loss so far.
As for the question you’ve asked, it really depends. Are you referring to stiffness in the calves afterwards, or burning in the calves during exercise?
If the burning occurs during cardio, I’d suggest that it’s simply a case of your calves growing accustomed to the increased level of activity. As muscular endurance increases, whilst the burning sensation may never completely disappear, the fact that regular cardio exercise improves the body’s ability to process oxygen, thus, improving the ability to handle rising blood lactate, you should find that the burning sensation becomes more tolerable.
Additionally, strengthening your calves (ideally through gym resistance), will also improve their muscular endurance, whilst also increasing the strength of the tendons in your lower leg, since they’ll also be loaded with weight as you work them in isolation.